Historically, the opposed-piston, two-stroke (OP2S) diesel engine set combined records for fuel efficiency and power density that have yet to be met by any other engine type. However, with modern emissions standards, wide-spread development of this engine for on-highway use stopped. At Achates Power, state-of-the-art analytical tools and engineering methods have produced an OP2S engine that, when compared to a leading medium-duty engine, has demonstrated a 21% fuel efficiency gain and engine-out emissions levels meeting U.S. EPA10 with conventional after-treatment. Among the presentation topics covered are thermodynamic efficiency, demonstrated engine results, cost and weight advantages, and overcoming two-stroke engine challenges. Presenter David Johnson, Achates Power Inc.